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  • Clinical Study
  • Outreach & Education
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2021

Seminar Series

Germline Programming and Epigenetic Inheritance

Schedule

Our seminars take place between 10:30-11:30 am PDT every other Tuesday via Zoom. Email us to get the link. 

Speakers

  • 16-Mar, Qi Chen, UCR, "Sperm RNA Code: How Many Bits of Information for Epigenetic Inheritance?"   


  • 30-Mar, Haifan Lin, Yale, "Uniting the Genome: Multi-Faceted Functions of piRNAs in the Germline".   


  • 27-Apr, Peter Snyder, Penn, "Efficacy of Testosterone Replacement in Older Hypogonadal Men".   


  • 11-May, Toshi Shioda, MGH/Harvard, "Pluripotent   Stem Cell-derived Cell Culture Models of Mammalian Primordial Germ Cells".   


  • 25-May, Jacquetta Trasler, McGill, "Uncovering Epigenetic Mechanisms of Intergenerational Disease through Studies of Perturbations in Folate Metabolism".


  • 8-Jun, Amander Clark, UCLA, "Differentiating Gametes from Pluripotent Stem Cells".   


  • 22-Jun, Anne Ferguson-Smith, Cambridge, "Mammalian Epigenetic Inheritance: Models and Mechanisms".
  • 02-Jul, Jingtao Guo, Univ. Utah, "Towards a Better Understanding of Human Germline and Testis Development".

 

Summer Fellowship Program

This year's Summer Fellowship Program will continue to be virtual. The detailed schedule is as follows: 


06/18 11:00-12:00 PM   Introduction  Dr. Wei Yan  

                                      Reproductive Function in Boys and Men.  Dr. Ronald Swerdloff   


06/25 1:00-2:00 PM      Sperm Maturation and Fertilization.  Dr. Christina Wang and Ms. Kawen Young   


07/02 1:00-2:00 PM      Genetics: Congenital Birth Defects and Genetic Diseases. Drs. Wei Yan and Peter Rivera   


07/06 1:00-2:00 PM      Epigenetics: What Is It, and Why Is It Important. Dr. John McCarrey and Ms. Felica Jones   


07/14 1:00-2:00 PM      Effects of Physical Activities on Epigenome and Genome. Dr. Harry Rossiter and Ms. Pluscedia Williams   


07/28 1:00-2:00 PM     Effects of Nutrition on Epigenome and Genome. Dr. Rachelle Bross and Ms. Audrey Alo   


08/02 1:00-2:00 PM     Epigenetic Inheritance. Dr. Qi Chen and Ms. Dominga Pardo   


08/4 1:00-2:00 PM       Single-cell analyses. Mr. Hayden McSwiggen and Ms. Felica Jones    

Recorded Lectures from the 2021 Summer Fellowship Program

Lectures on YouTube

2020

Outreach and Education

Our 2020 Sumer Fellowship Program was a great success!  A total of 83 students from diverse ethic/racial and socio-economic backgrounds enrolled in the summer program. The attendance form each session was over 80%. The students came from 39 schools and were residents of 40 cities within Los Angeles County.  


Due to the COVID19 pandemic the in-person Summer Fellowship Program was converted to virtual seminars. Academic investigators from the Center met with community members to plan the 8 lectures to introduce the students and our community members to male reproductive physiology, spermatogenesis, genetics and epigenetics, lifestyle modifications and bioinformatics in reproductive science. One-on-one meetings and rehearsals were set up such that slides, videos, and questions for the students are reviewed jointly by our community and academic partners. Many of the Center researchers have not partnered with community members before including those from University of Nevada, Reno, University of Texas at San Antonio and University of California Riverside as well as some of the Lundquist investigators. The theme of the series was “Healthy Life Style, Healthy Sperm, Healthy Children”. Within the lecture, questions were posted and the students responded to questions to ensure participation of the students. Gauging by the questions that were posted in the chat room after the session, the students were following the seminars attentively. This is our attempt to apply the principles of “Community Partnered Participatory Research” to education and teaching. The series was unique for the partnership of community members with academics from a wide range of disciplines: basic and clinical researchers, nutritionists, exercise physiologists and bioinformaticians to introduce male reproductive biology, genetics, and epigenetics.  


The 8 lectures can be accessed through Vimeo.  Evaluation of the course by the student demonstrated over 90% agreed that the course provided appropriate information, was overall effective, well organized with clear presentation and style. The speakers and the organizers also provided a self-assessment of the group meetings and one-on-one sessions between community members and investigators. Most agreed that there was trust between the groups, bridges were being built, and members worked well together. There was only a slight dominance of the investigators in the workgroup and in decision making which was not unexpected because of the science-driven themes of the talks (Figure 2). Overall the speakers, community members and organizers thought that this was a very good experience with bidirectional knowledge transfer of knowledge during development of the slides and presentations. Interactions between academia and community were rated favorably by students. 

National Center for Male Reproductive Epigenomics

1124 W Carson St, Torrance, CA 90502

(775) 338-9885

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